A high-throughput, high-resolution imager for multi-fluorescence imaging of 3D and 2D cultured cells.

Description

Research field

  • Quantification and analysis for organoids, spheroids and general 2D cultured cells

  • Cancer drug research and regenerative medicine

High-end model for both 2D and 3D culture analysis

  • Possible to observe laminar cells such as epithelial cells clearly at the same level as phase-contrast microscope

  • A high-throughput imager for a variety of applications such as single cell cloning, ES/iPS cell and  organoids morphology analysis

  • Function enhancement by plug-in software

  • Automation systems (optional)

 

​Multi-fluorescence imaging / High-throughput

  • 1 minute to scanning and 30 seconds analyzing

  • ​Multi-fluorescence imaging and analysis available​(Optional)

Features

1. Multi-fluorescence imaging and analysis

  • Multi-fluorescence imaging and analysis

  • Bright field and 3 fluorescent colors are automatically and continuously imaged with the simultaneous loading of LED fluorescent filter

  • ​Line up of 5 types of fluorescent filters

2.  Meniscus-less

Less meniscus and clear imaging even at the peripheral area

Bright field

Detect those areas

  • Unique hyper-centric and tele-centric optical systems enables a high-resolution imaging of whole well including the marginal area of well

  • Lens have 2 resolution which has 0.8um/pix and 4um/pix

  • ​Equipped with high accurate extraction algorithm even cells soon after seeing

  • High speed mode provide 60 sec/ 96 well plate and 70 sec/ 384 well plate.

3. Deep Learning Plug-in (optional)

image courtesy of Prof. Yun Chen,Far Eastern Memorial Hospital, TW

4. Neurite elongation plug-in (optional) 

  • Multi-object analysis, such as neurite elongation, is provided as a plug-in software

Cell body  ,  Neurite

  • Deep Learning to extract and quantify only grown organoids

  • High confluence and non-uniform images can be accurately extracted and measured using Deep Learning

5. 3D cellular imaging

  • Equipped with a proprietary lens with a deep depth of field suitable for 3D cultured cell imaging and illumination

  • Z-stacking imaging and focus composition functions

  • Compatible with F-bottom, V-bottom, U-bottom, various SBS formats and microwell plates as standard

  • Functional specialty plates such as plates for 3D culture, Corning® Elplasia® (Corning Japan) and EZSPHERE (AGC Techno Glass Co., Ltd.) are also available

6. Automation system

  • Automation by connecting external devices such as plate stacker and incubator with a plate transfer robot

  • Automatically captures up to 200 images per day by robotization, streamlining a complicated workflow

​Specification

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