A bright field spheroid counter,
allowing reagent-free follow-up and
3D culture based-drug discovery and regenerative medicine research
Non-invasive research that researchers cannot fix/stain cultured cells
54 second scan time per 1 micro well plate
90 seconds for spheroids counting and quantifying area, diameter
and pseudo volume for each spheroid
Entry model for 3D culture analysis
Entry model and optimized for 3D culture analysis and bright-field imaging
1. High-throughput bright field scanners for 3D spheroids
Cell3iMagers are bright field scanners designed specifically to simplify and accelerate quantitative and qualitative measurement of 3D spheroids.
This unique LED-based imaging system allows the user to identify and measure single or multiple spheroids per well in a microplate rapidly and automatically.
The companion 3D optimized analysis software allows faster image capture, measurement and data analysis
2. Z-stucking of 3D cellular structures
Cell3iMager has a focus composite function.
Merge stacking images of each Z-direction, for example gel culture or soft agar medium.
Measure/quantify mass of cells spread in the Z-direction at once
3. Compatible with various 3D culture microplates
Clear-wall U-shape bottom
Thermo Fisher Scientific, NOF
Clear-wall flat bottom
Black-wall flat bottom
Stained 2D cultured cell
Cancer cell proliferation in soft agar medium
Neurospheres in suspension culture
Intestinal epithelial cells organoids
Spheres cultured in U-shaped well
Compatible with a wide variety of 3D culture microplates
4. Intelligent 3D software
Supports basic (single-time point) and time-course dose-response analysis, as well as a multi-planar (focus bracketing) scanning option to use with hydrogel-embedded spheroids
30+ adjustable parameters for optimizing object identification, live/dead discrimination (e.g., bubbles, fibers, debris), and compensate for edge of well shadows and distortion as well as reduction of background noise
Identify and measure microtissues in single spheroid per well or multiple spheroid per well formats